True 360º isotropic resolution

Increased axial resolution

Improved spatial resolution

Speed

Structural information

True 360º isotropic resolution

Our QLS-scope is the only optical device with a patented technology (SPOT) that can generate 3D fluorescence images with high spatial (<1 µm) and axial (< 1 µm) resolution, at 360º and for large cleared fixed samples (1 – 20 mm). For more information please check our Isotropic Resolution technology section.

For very transparent fixed and cleared samples, sometimes is enough to make SPIM measurements in two (0 and 180 degrees) or four (0, 90, 180 and 270 degrees) angles and recombine the images to create a 3D image. Our Hummingbird software is the only one capable of reconstructing images of SPIM of up to 4 angles of large (1-20mm) cleared samples.

Increased axial resolution

Improved spatial resolution

The excitation Rayleigh range of the light sheet, in most cases, is smaller than the FOV needed to image large cleared and fixed samples.

Our Sweep mode tiles multiple ROI image stacks, with axially displaced light sheets, to generate images with the best spatial resolution across the whole FOV. 

For more information please check our Spatial Resolution technology section.

For large cleared samples if you are looking for either a larger field of view (stitching), a better spatial resolution (Sweep) or isotropic resolution through angular measurements (2, 4 or 500 angles), you need a very high measuring speed. The QLS-scope is the fastest Light Sheet microscope in the market. For more information please check our Increased Speed technology section.

Structural information

Our QLS-scope is the only commercially available system that can provide Optical Projection Tomography (OPT) data that can be used to observe the entire anatomy of a sample, combined with specific sample information from Selective Plane Imaging Microscopy (SPIM). For more information please check our SPIM-OPT technology section.