Technology QLS
QLS-Clear Reagents
Our optical clearing reagents are designed to deliver reliable, high-quality tissue transparency while preserving structural integrity and compatibility with fluorescence imaging. Together, they form a robust and versatile solution for 3D imaging of biological samples across a wide range of sizes and tissue types.
QLS-R1 — Efficient Lipid Removal
QLS-R1 is a dedicated lipid-removal reagent that effectively clears light-scattering lipids while maintaining tissue architecture. It enables deep optical access to dense biological structures, preparing samples for high-contrast volumetric imaging.
QLS-R2 — Refractive Index Matching
QLS-R2 is a refractive-index-matching reagent optimized to homogenize optical properties throughout the cleared tissue. By minimizing residual light scattering and aberrations, R2 ensures uniform transparency and optimal imaging performance, even in large or heterogeneous samples.
Broad Sample Compatibility
Our optical clearing reagents are suitable for a wide range of biological specimens, including:
- Mouse organs such as brain, kidney, lung, heart, liver, etc.
- Early-stage mouse embryos
- Human biopsy samples
Their formulation supports consistent clearing results across soft and dense tissues alike.
Optimized for Automation
Both reagents are specifically designed for seamless use with our automated optical clearing device QLS-Clear, enabling reproducible, hands-free clearing workflows. This combination reduces manual handling, improves process consistency, and accelerates sample preparation for high-throughput imaging applications.
