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Optical Clearing & 3D Imaging 

We offer a complete end-to-end service portfolio for optical clearing, immunostaining, and high-resolution 3D imaging of biological tissues. Our workflows are optimized for consistency, image quality, and compatibility with advanced volumetric microscopy techniques

Optical Clearing Service

Our optical clearing service provides efficient and reproducible tissue transparency for a wide range of biological samples. Using optimized clearing protocols and controlled processing conditions, we enable deep optical access while preserving tissue morphology and fluorescence compatibility.

Suitable for:

  • Whole organs and tissue sections
  • Mouse tissues (brain, kidney, lung, heart, liver, etc.)
  • Early-stage mouse embryos
  • Plants
  • Insects

Optical Clearing & Immunostaining

This service combines tissue clearing with deep, homogeneous immunolabeling, allowing specific molecular targets to be visualized throughout large 3D volumes.

Key advantages:

  • Uniform labeling in large and dense tissues
  • Compatibility with cleared samples
  • Preservation of structural and molecular information
  • Wide range of antibodies

 

3D Imaging with LSFM / SPIM

We provide high-quality 3D fluorescence imaging using Light-Sheet Fluorescence Microscopy (LSFM/SPIM). This technique enables fast volumetric acquisition with low photobleaching and phototoxicity, making it ideal for large cleared samples.

 

Imaging capabilities include:

  • Rapid acquisition of large 3D datasets
  • High contrast and optical sectioning
  • 3D Imaging of cleared organs and embryos
  • Stractural and specific internal information at the same image stack

End-to-End Workflow: Clearing, Immunostaining & 3D Imaging

For customers seeking a fully integrated solution, we offer a complete workflow from sample preparation to final 3D image acquisition.

This turnkey service includes:

  • Optical clearing using optimized reagents and protocols
  • Immunostaining tailored to the target markers
  • 3D imaging and dataset delivery in standard formats

 

Why Choose Our Services?

  • Reproducible and standardized workflows
  • Compatibility with large and delicate samples
  • Expertise in optical clearing and volumetric imaging
  • Seamless integration with automated clearing technologies